Tokumitsu M, Inada F, Kitahara K, Kawakami N, Masui N, Ishida H, Ishida H, Saga Y, Hashimoto H, Yachiku S
Department of Urology, Ishida Hospital.
Hinyokika Kiyo. 2001 Jan;47(1):59-62.
Prostatic cancer is rarely diagnosed by detection of lung metastases. We report a case of prostatic cancer in a 73-year-old man detected by abnormalities in chest X-ray and serum prostate specific antigen (PSA) level. He was initially admitted to our hospital due to elevation of PSA level. On the first transperineal prostatic needle biopsy, prostatic cancer was not detected and he was followed. Seven months after the first biopsy, chest X-ray revealed multiple abnormal nodules in the lung fields bilaterally and PSA level was again elevated. A second prostatic biopsy and whole-body examination were performed, and he was diagnosed with moderately differentiated prostatic adenocarcinoma with multiple lung metastases. Complete androgen blockade therapy was performed immediately. Two months after the beginning of treatment, PSA level was normalized and the multiple lung metastases had completely disappeared. There has been no evidence of recurrence or PSA relapse 24 months after detection of the prostatic cancer. This is the 26th case of prostatic cancer diagnosed in Japan following detection of multiple lung metastases.
前列腺癌很少通过检测肺转移来诊断。我们报告一例73岁男性前列腺癌病例，该病例通过胸部X线异常和血清前列腺特异性抗原（PSA）水平检测发现。他最初因PSA水平升高入住我院。首次经会阴前列腺穿刺活检未检测到前列腺癌，对其进行随访。首次活检7个月后，胸部X线显示双肺野多发异常结节，PSA水平再次升高。进行了第二次前列腺活检和全身检查，他被诊断为中度分化前列腺腺癌伴多发肺转移。立即进行了完全雄激素阻断治疗。治疗开始2个月后，PSA水平恢复正常，多发肺转移完全消失。前列腺癌确诊24个月后，没有复发或PSA复发的证据。这是日本第26例在检测到多发肺转移后诊断出的前列腺癌病例。
