Kuflik A, Stillo J V, Sanders D, Roland K, Sweeney T, Lemke P M
Adult and Child Dermatology Center, Lakewood, NJ, USA.
Ostomy Wound Manage. 2001 Feb;47(2):52-6.
This study compares the therapeutic effects of a new topically applied, nonprescription medication that has been introduced for re-epithelialization of ulcers and erosions of the skin, with petrolatum in treating pressure ulcers of shallow depth (Stage I and Stage II). A 6-week, randomized, double-blind study was performed on 19 patients with Stage I or Stage II pressure ulcers. The patients received either the new nonprescription medication or petrolatum, which served as a control. After the course of the study, the study ointment effected resolution in a majority of pressure ulcers (9 out of 10), while only one out of three ulcers treated with petrolatum resolved in the same time period. These preliminary results show that the study ointment is a safe and effective treatment for Stage I and II pressure ulcers.
本研究比较了一种新的局部应用的非处方药物与凡士林在治疗浅度压疮（I期和II期）方面的疗效。该非处方药物已被用于促进皮肤溃疡和糜烂的上皮再形成。对19例I期或II期压疮患者进行了一项为期6周的随机双盲研究。患者分别接受这种新的非处方药物或作为对照的凡士林治疗。在研究过程结束后，研究用软膏使大多数压疮（10例中的9例）得到愈合，而在同一时期，用凡士林治疗的3例溃疡中只有1例愈合。这些初步结果表明，该研究用软膏是治疗I期和II期压疮的一种安全有效的疗法。
