Gielerak G, Michałkiewicz D, Makowski K, Jacewicz K, Gniłka A, Cholewa M, Adamus J
Klinika Chorób Wewnetrznych i Kardiologii Centralnego Szpitala Klinicznego Wojskowej AM w Warszawie.
Pol Arch Med Wewn. 2000 Jan-Feb;103(1-2):73-8.
Vasovagal syncope is a complex syndrome in which specific methods of treatment rarely are related to clinical success. Since it turned out that some patients with neurocardiogenic syncope were resistant to offered pharmacotherapy, cardiac pacing has been used as the alternative way of long-term therapy. Successive studies, which have estimated clinical efficacy of permanent cardiac pacing, indicate that such method of treatment may reduce symptoms revealed by vasovagal reflex. Nevertheless the optimal pacing mode has not been established yet. It is known that single chamber VVI pacing is not a good and effective method whereas dual chamber DDI pacing with rate hysteresis seems to be very promising in treatment of people suffering from malignant cardioinhibitory vasovagal syncope. DDD pacing with rate drop response, search and scan functions recently has been available to these patients. The results of the North American Vasovagal Pacemaker Study, as well as some casuistic observations referring to patients with vasovagal syndrome, show very high clinical efficacy of dual chamber pacing with mentioned new functions. We present a case of patient with cardioinhibitory vasovagal syncope who was successfully treated by permanent DDD pacing with search and scan hysteresis.
血管迷走性晕厥是一种复杂的综合征,其中特定的治疗方法很少能带来临床成功。由于发现一些神经心源性晕厥患者对所提供的药物治疗有抵抗性,心脏起搏已被用作长期治疗的替代方法。一系列评估永久性心脏起搏临床疗效的研究表明,这种治疗方法可能会减轻血管迷走反射所揭示的症状。然而,最佳的起搏模式尚未确定。已知单腔VVI起搏不是一种良好有效的方法,而具有频率滞后的双腔DDI起搏在治疗恶性心脏抑制性血管迷走性晕厥患者方面似乎非常有前景。具有频率骤降反应、搜索和扫描功能的DDD起搏最近已应用于这些患者。北美血管迷走性起搏器研究的结果以及一些关于血管迷走综合征患者的个案观察表明,具有上述新功能的双腔起搏具有非常高的临床疗效。我们报告一例心脏抑制性血管迷走性晕厥患者,通过具有搜索和扫描滞后功能的永久性DDD起搏成功治疗。