Golledge P, Knight C J
London Chest Hospital, London E2 9JX.
Hosp Med. 2001 Feb;62(2):79-82. doi: 10.12968/hosp.2001.62.2.1524.
Hypertrophic cardiomyopathy is a familial cardiac disorder with heterogeneous expression and a diversity of morphological, functional and clinical features. Some individuals with hypertrophic cardiomyopathy may be asymptomatic while others are disabled by symptoms of angina and breathlessness. This article summarizes the genetics, pathophysiology and present management of this important condition.
肥厚型心肌病是一种具有异质性表达以及形态、功能和临床特征多样性的家族性心脏疾病。一些肥厚型心肌病患者可能没有症状,而另一些患者则因心绞痛和呼吸急促症状而丧失活动能力。本文总结了这种重要疾病的遗传学、病理生理学及目前的治疗方法。