Xie J X, Zhou Y, Jiang H
Department of Physiology, Medical College of Qingdao University, Qingdao 266021.
Zhongguo Ying Yong Sheng Li Xue Za Zhi. 2000 Nov;16(4):370-2.
Using fast cyclic voltammetry (FCV) and carbon fibre microelectrode (CFMe), we monitored dopamine (DA) release from caudate putamen(CPu), nucleus accumbens(Acb) and central amygdaloid nucleus(CAN) of normal rats in vivo, in order to find out the suitable parameters to evoke DA release of certain area. DA release was evoked by electrical stimulation of medial forebrain bundle(MFB) or ventral tegmental area(VTA).
DA release from CPu, Acb or CAN were different in contents and the characteristics of dynamics.
Different parameters should be used according to the different sites of stimulation in order to get the maximal DA release during the experiment.
运用快速循环伏安法（FCV）和碳纤维微电极（CFMe），我们在体内监测正常大鼠尾壳核（CPu）、伏隔核（Acb）和中央杏仁核（CAN）的多巴胺（DA）释放情况，以找出能诱发特定区域DA释放的合适参数。通过电刺激内侧前脑束（MFB）或腹侧被盖区（VTA）来诱发DA释放。
CPu、Acb或CAN释放的DA在含量和动力学特征上存在差异。
实验过程中，应根据不同的刺激部位采用不同参数，以实现DA的最大释放。
