Taylor S J, Whincup P H, Hindmarsh P C, Lampe F, Odoki K, Cook D G
Department of General Practice and Primary Care, St Bartholomew's and the Royal London School of Medicine and Dentistry, Queen Mary and Westfield College, UK.
Paediatr Perinat Epidemiol. 2001 Jan;15(1):88-94. doi: 10.1046/j.1365-3016.2001.00317.x.
We describe the performance of a new, self-assessment questionnaire that aims to measure pubertal status by using gender-specific line drawings of the Tanner puberty stages. The study was carried out on 103 children aged 12-16 years attending a paediatric endocrinology outpatient clinic and used physical examination by clinic doctors as the 'gold standard'. Of 133 consecutive, eligible children, 108 (81%) agreed to participate in the study. Data were collected from 62 (60%) males and 41 (40%) females. Mean age was 14.78 years (SD = 1.26 years, range 12.08-16.98 years). For the pubic hair distribution Tanner stage, there was agreement to within one Tanner stage for 90 children (88%), weighted kappa statistic for inter-rater agreement = 0.68 [95% CI 0.49,0.87]. For the female breast/male genitalia Tanner stage, there was agreement to within one Tanner stage for 75 children (76%), kappa = 0.48 [95% CI 0.31,0.64]. The children tended to underestimate their stage of pubertal development. Overall, the kappa statistics implied good agreement for the pubic hair question and moderate agreement for the breast/genitalia stage question in both girls and boys. The questionnaire may prove useful in situations such as large-scale epidemiological studies, in which direct examination of children to determine pubertal status is not possible, and further validation in normal adolescents is warranted.
我们描述了一种新的自我评估问卷的性能,该问卷旨在通过使用坦纳青春期阶段的性别特异性线条图来测量青春期状态。该研究对103名年龄在12至16岁之间、前往儿科内分泌门诊就诊的儿童进行,以临床医生的体格检查作为“金标准”。在133名连续符合条件的儿童中,108名(81%)同意参与研究。收集了62名(60%)男性和41名(40%)女性的数据。平均年龄为14.78岁(标准差=1.26岁,范围12.08 - 16.98岁)。对于阴毛分布的坦纳阶段,90名儿童(88%)的评估结果在一个坦纳阶段内一致,评分者间一致性的加权kappa统计量 = 0.68 [95%置信区间0.49,0.87]。对于女性乳房/男性生殖器的坦纳阶段,75名儿童(76%)的评估结果在一个坦纳阶段内一致,kappa = 0.48 [95%置信区间0.31,0.64]。儿童往往低估自己的青春期发育阶段。总体而言,kappa统计量表明,在男孩和女孩中,阴毛问题的一致性良好,乳房/生殖器阶段问题的一致性中等。该问卷在诸如大规模流行病学研究等情况下可能有用,在这些研究中无法直接检查儿童以确定青春期状态,因此有必要在正常青少年中进行进一步验证。