• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

雌激素和孕酮对体外培养的小鼠子宫中氚标记胸腺嘧啶核苷掺入的影响。

The effect of oestrogen and progesterone on the incorporation of tritiated thymidine in mouse uteri in vitro.

作者信息

Carter J, McLaren A

出版信息

J Reprod Fertil. 1975 Mar;42(3):439-45. doi: 10.1530/jrf.0.0420439.

DOI:10.1530/jrf.0.0420439
PMID:1123812
Abstract

The incorporation of tritiated thymidine into the uteri of immature mice in organ culture was assessed by autoradiography and liquid scintillation spectrometry. Oestrogenand progesterone, alone or combined, stimulated an increase in the incorporation of tritiated thymidine, indicating that DNA synthesis is occurring in vitro. Progesterone alone stimulated incorporation of label into stromal and epithelial cells, but the combination of progesterone and oestrogen stimulated the labelling of epithelial cells more than of stromal cells.

摘要

通过放射自显影术和液体闪烁光谱法评估了在器官培养中氚标记胸腺嘧啶核苷掺入未成熟小鼠子宫的情况。单独或联合使用雌激素和孕酮可刺激氚标记胸腺嘧啶核苷掺入量增加,表明体外发生了DNA合成。单独使用孕酮可刺激标记物掺入基质细胞和上皮细胞,但孕酮和雌激素联合使用时对上皮细胞的标记作用比对基质细胞的更强。

相似文献

1
The effect of oestrogen and progesterone on the incorporation of tritiated thymidine in mouse uteri in vitro.雌激素和孕酮对体外培养的小鼠子宫中氚标记胸腺嘧啶核苷掺入的影响。
J Reprod Fertil. 1975 Mar;42(3):439-45. doi: 10.1530/jrf.0.0420439.
2
Effects of oestradiol-17-beta and progesterone on total and nuclear-protein synthesis in epithelial and stromal tissues of the mouse uterus, and of progesterone on the ability of these tissues to bind oestradiol-17-beta.17-β-雌二醇和孕酮对小鼠子宫上皮和基质组织中总蛋白和核蛋白合成的影响,以及孕酮对这些组织结合17-β-雌二醇能力的影响。
Biochem J. 1970 Oct;119(4):773-84. doi: 10.1042/bj1190773.
3
The effects of oestrogen on the cell cycle in epithelial and connective tissues of the mouse uterus.雌激素对小鼠子宫上皮组织和结缔组织细胞周期的影响。
J Endocrinol. 1972 Oct;55(1):21-30. doi: 10.1677/joe.0.0550021.
4
Estrogenic effects of the antiprogestin onapristone (ZK98.299) in the rodent uterus.抗孕激素奥那司酮(ZK98.299)对啮齿动物子宫的雌激素样作用。
Am J Obstet Gynecol. 1994 Jul;171(1):188-94. doi: 10.1016/0002-9378(94)90468-5.
5
Culture characteristics of human endometrial glandular epithelium throughout the menstrual cycle: modulation of deoxyribonucleic acid synthesis by 17 beta-estradiol and medroxyprogesterone acetate.整个月经周期中人类子宫内膜腺上皮的培养特性:17β-雌二醇和醋酸甲羟孕酮对脱氧核糖核酸合成的调节
Am J Obstet Gynecol. 1992 Dec;167(6):1888-98. doi: 10.1016/0002-9378(92)91792-9.
6
Synergism between prolactin and ovarian hormones of DNA synthesis in rats mammary gland.
Proc Soc Exp Biol Med. 1975 May;149(1):189-92. doi: 10.3181/00379727-149-38770.
7
Effects of progestins and glucocorticoids on deoxyribonucleic acid synthesis in the uterus of the neonatal mouse.孕激素和糖皮质激素对新生小鼠子宫中脱氧核糖核酸合成的影响。
Endocrinology. 1985 Dec;117(6):2520-6. doi: 10.1210/endo-117-6-2520.
8
Autoradiographic studies on the influence of gestagens on oestrogen-induced incorporation of 3H-uridine and 3H-thymidine into nucleic acids of the rat uterus.关于孕激素对雌激素诱导的3H-尿苷和3H-胸腺嘧啶核苷掺入大鼠子宫核酸的影响的放射自显影研究。
Gynecol Invest. 1973;4(3):155-64. doi: 10.1159/000301719.
9
Kinetics of DNA synthesis in immature rat uterus: age dependence and estradiol stimulation.未成熟大鼠子宫中DNA合成的动力学:年龄依赖性和雌二醇刺激
Biochim Biophys Acta. 1971 Feb 28;261(2):475-86. doi: 10.1016/0304-4165(72)90072-4.
10
Synthesis of DNA and mitosis in rabbit uteri after oestrogen and progesterone injections, and during early pregnancy.
J Reprod Fertil. 1972 Dec;31(3):473-6. doi: 10.1530/jrf.0.0310473.