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Role for HLA class II molecules in HIV-1 suppression and cellular immunity following antiretroviral treatment.人类白细胞抗原II类分子在抗逆转录病毒治疗后HIV-1抑制及细胞免疫中的作用
J Clin Invest. 2001 Feb;107(4):505-17. doi: 10.1172/JCI11275.
2
Proliferative responses to human immunodeficiency virus type 1 (HIV-1) antigens in HIV-1-infected patients with immune reconstitution.免疫重建的HIV-1感染患者对1型人类免疫缺陷病毒（HIV-1）抗原的增殖反应。
J Infect Dis. 2001 Feb 15;183(4):657-61. doi: 10.1086/318545. Epub 2001 Jan 12.
3
Immune control of HIV-1 after early treatment of acute infection.急性感染早期治疗后HIV-1的免疫控制
Nature. 2000 Sep 28;407(6803):523-6. doi: 10.1038/35035103.
4
HLA B*5701 is highly associated with restriction of virus replication in a subgroup of HIV-infected long term nonprogressors.HLA B*5701与HIV感染的长期非进展者亚组中病毒复制的受限高度相关。
Proc Natl Acad Sci U S A. 2000 Mar 14;97(6):2709-14. doi: 10.1073/pnas.050567397.
5
Effect of combination antiretroviral therapy on T-cell immunity in acute human immunodeficiency virus type 1 infection.联合抗逆转录病毒疗法对急性1型人类免疫缺陷病毒感染中T细胞免疫的影响。
J Infect Dis. 2000 Jan;181(1):121-31. doi: 10.1086/315202.
6
Levels of human immunodeficiency virus type 1-specific cytotoxic T-lymphocyte effector and memory responses decline after suppression of viremia with highly active antiretroviral therapy.高效抗逆转录病毒疗法抑制病毒血症后，1型人类免疫缺陷病毒特异性细胞毒性T淋巴细胞效应和记忆反应水平下降。
J Virol. 1999 Aug;73(8):6721-8. doi: 10.1128/JVI.73.8.6721-6728.1999.
7
Consistent associations of HLA class I and II and transporter gene products with progression of human immunodeficiency virus type 1 infection in homosexual men.人类免疫缺陷病毒1型感染在男同性恋者中进展与HLA I类和II类以及转运蛋白基因产物的持续关联。
J Infect Dis. 1999 Aug;180(2):299-309. doi: 10.1086/314862.
8
Control of HIV despite the discontinuation of antiretroviral therapy.尽管停止了抗逆转录病毒治疗，但HIV仍得到控制。
N Engl J Med. 1999 May 27;340(21):1683-4. doi: 10.1056/NEJM199905273402114.
9
HIV-1-specific CD4+ T cells are detectable in most individuals with active HIV-1 infection, but decline with prolonged viral suppression.在大多数处于活跃HIV-1感染期的个体中可检测到HIV-1特异性CD4+ T细胞，但随着病毒抑制时间延长，这些细胞数量会下降。
Nat Med. 1999 May;5(5):518-25. doi: 10.1038/8400.
10
HLA and HIV-1: heterozygote advantage and B*35-Cw*04 disadvantage.人类白细胞抗原与人类免疫缺陷病毒1型：杂合子优势及B*35-Cw*04劣势
Science. 1999 Mar 12;283(5408):1748-52. doi: 10.1126/science.283.5408.1748.

MHC class II genotype and the control of viremia in HIV-1-infected individuals on highly active antiretroviral therapy.

作者信息

Blankson J N, Siliciano R F

机构信息

Johns Hopkins University School of Medicine, Department of Medicine, Baltimore, Maryland, USA.

出版信息

J Clin Invest. 2001 Mar;107(5):549-51. doi: 10.1172/JCI12430.

DOI:10.1172/JCI12430
PMID:11238554
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC199437/
Abstract
摘要