Solomina S N, Sorokina T N
Kardiologiia. 1975 Feb;15(2):46-8.
Puncture biopsy of the liver and a comparison of the blood serum enzymes-lactate-dehydrogenase and fructose-1-phosphate-aldolase-with the nature of histomorphological alterations were effected in 18 patients with rheumatic heart diseases, circulatory insufficiency of the II-III degree and rheumatism in the I-II stage of activity. Morphological changes in the liver were not specific, being characterized largely by congestive manifestations and deranged intrahepatic circulation. With a declining level of glycogen and nucleoproteins in the hepatocytes the blood serum of such patients showed an increased content of fructose-1-phosphate-aldolase and lactate-dehydrogenase. Histomorphological analysis of the puncture material facilitate the evaluation of the nature of intravital changes in the liver of patients with different degrees of circulatory insufficiency.
对18例患有风湿性心脏病、II - III度循环功能不全以及处于I - II期活动期风湿症的患者进行了肝脏穿刺活检，并将血清酶（乳酸脱氢酶和1 - 磷酸果糖醛缩酶）与组织形态学改变的性质进行了比较。肝脏的形态学变化并不具有特异性，主要表现为充血症状和肝内循环紊乱。随着肝细胞中糖原和核蛋白水平的下降，这些患者的血清中1 - 磷酸果糖醛缩酶和乳酸脱氢酶的含量增加。对穿刺材料的组织形态学分析有助于评估不同程度循环功能不全患者肝脏活体变化的性质。
