Bart B I, Gratsianskiĭ N A
Kardiologiia. 1975 Feb;15(2):84-9.
The activity of glutamino-oxaloacetic transaminase was studied in 85 and that of creatinophosphokinase, total lactate-dehydrogenase and its isoenzymes in 58 patients with macrofocal myocardial infarction complicated by a shock. The maximal transaminase activity in patients with myocardial infarction attended by a shock was on the average greater than in similar patients without any shock. In patients with myocardial infarction attended by a shock who presented, at the same time, congestive manifestations in the systemic ciruclation demonstrated a higher transaminase activity and its normalization at a later date than this was in the case of patients with a shock, but without congestion in the systemic circulation. In patients suffering from myocardial infarction with a shock the activity of creatinophosphokinase and total lactate-dehydrogenase averaged higher than in those without shock. In the blood serum of such patients the proportions of the lactate-dehydrogenase isoenzymes were found to undergo substantial changes, which consisted in an increased activity of the LDH1 and LDH5 fractions. The main factor responsible for a considerable rise in the activity of the blood serum transaminase, creatinophosphokinase, total lactate-dehydrogenase and the LDH1 fraction occurring in patients with myocardial infarction attended by a shock is the great extent of the necrotic focus in the myocardium.
对85例合并休克的大片灶性心肌梗死患者的谷草转氨酶活性进行了研究，并对58例此类患者的肌酸磷酸激酶、总乳酸脱氢酶及其同工酶进行了研究。合并休克的心肌梗死患者的转氨酶活性最大值平均高于无休克的类似患者。合并休克且同时出现体循环充血表现的心肌梗死患者，其转氨酶活性更高，且与无体循环充血的休克患者相比，其转氨酶活性恢复正常的时间更晚。合并休克的心肌梗死患者的肌酸磷酸激酶和总乳酸脱氢酶活性平均高于无休克者。在这类患者的血清中，发现乳酸脱氢酶同工酶的比例发生了显著变化，表现为LDH1和LDH5组分活性增加。合并休克的心肌梗死患者血清转氨酶、肌酸磷酸激酶、总乳酸脱氢酶和LDH1组分活性大幅升高的主要因素是心肌坏死灶范围较大。
