氨基核苷肾病中肾小球上皮细胞间连接的冰冻断裂研究。
A freeze-fracture study of the junctions between glomerular epithelial cells in aminonucleoside nephrosis.
作者信息
Ryan G B, Leventhal M, Karnovsky M J
出版信息
Lab Invest. 1975 Mar;32(3):397-403.
PMID:1123915
Abstract
In rats with aminonucleoside nephrosis, glomerular slit pores are mostly replaced by sites of close apposition between adjacent epithelial cell membranes. In replicas of freeze-fractured glomeruli, such junctions showed incomplete fibrils or grooves typical of "leaky" zonulae occludentes.
摘要
在氨基核苷肾病大鼠中，肾小球裂孔大多被相邻上皮细胞膜紧密贴合的部位所取代。在冷冻断裂肾小球的复制品中，这种连接显示出典型“渗漏”紧密连接的不完整纤维或沟。
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