Ortega-Rodriguez E, Levy-Marchal C, Guillermine S, Polak M
Pediatric Endocrine and Diabetes Unit, INSERM U457, Robert Debré Hospital, Paris, France.
Diabetes Metab. 2001 Feb;27(1):59-61.
We present the case of a well characterised M.O.D.Y. type 2 diabetes family in which one of the children associated beta cell autoimmunity and a HLA DQB1 at risk for immune-mediated type 1 diabetes mellitus. The search for autoantibodies against beta cell should be considered in cases of genetically defined form of diabetes mellitus to exclude the possibility of a concomitant risk to develop type 1 diabetes mellitus.
我们报告了一个特征明确的青少年发病的成年型糖尿病2型（M.O.D.Y. 2）糖尿病家族病例，该家族中的一名儿童同时存在β细胞自身免疫以及与免疫介导的1型糖尿病风险相关的HLA DQB1。对于基因明确的糖尿病病例，应考虑检测针对β细胞的自身抗体，以排除同时存在发生1型糖尿病风险的可能性。
