Robbins J B, Reinisch L, Ellis D L
Department of Medicine (Division of Dermatology), Vanderbilt University and Nashville Veterans Affairs Medical Centers, Nashville, Tennessee 37232-5227, USA.
Lasers Surg Med. 2001;28(2):162-7. doi: 10.1002/lsm.1034.
We sought to optimize laser incisions by evaluating the effects of varying the slit width of a heat-conducting template and the step size with the Computer-Assisted Surgical Techniques (CAST) system on free electron laser (FEL) incisions at 6.45 microm.
STUDY DESIGN/MATERIALS AND METHODS: Stainless steel calipers were used as a heat-conducting template on human skin in vitro. The CAST system made the incisions as a series of spot ablations with set step sizes of 50 microm or 1,250 microm. At each step size, incisions were made with or without the calipers, by using varying slit widths. Histologic specimens were analyzed for lateral thermal damage over the entire depth of the incision and over the superficial 150 microm of dermis.
Lateral thermal damage over the superficial 150 microm of dermis was most significantly reduced with the calipers at a slit width approximating the FEL's beam diameter (636 microm +/- 100 microm). Also, incisions made with the larger step size (1,250 microm) had significantly less lateral thermal damage over the entire depth of the incision.
The use of a heat-conducting template with an aperture approximating the FEL's beam diameter and larger step size improved FEL incisions at 6.45 microm.
我们试图通过评估导热模板的狭缝宽度变化以及计算机辅助手术技术(CAST)系统的步长对6.45微米自由电子激光(FEL)切口的影响,来优化激光切口。
研究设计/材料与方法:在体外人体皮肤上,使用不锈钢卡尺作为导热模板。CAST系统以50微米或1250微米的设定步长进行一系列点状消融来制作切口。在每个步长下,使用不同的狭缝宽度,分别在有或没有卡尺的情况下制作切口。对组织学标本进行分析,以评估切口全层以及真皮浅层150微米范围内的侧向热损伤情况。
在真皮浅层150微米范围内,当狭缝宽度接近FEL光束直径(636微米±100微米)时,使用卡尺可使侧向热损伤显著降低。此外,采用较大步长(1250微米)制作的切口在切口全层的侧向热损伤明显更少。
使用孔径接近FEL光束直径且步长较大的导热模板可改善6.45微米的FEL切口。