Barreras R F
Postgrad Med. 1975 Apr;57(4):121-4. doi: 10.1080/00325481.1975.11714016.
The antacids and anticholinergics should be considered potent pharmacologic agents with potentially serious side effects. When the conditions constituting major contraindications to these forms of therapy have been considered and their presence has been ruled out, the antacids and anticholinergics are useful in managing the symptoms and course of disease due to the effects of acid and pepsin. Antacid given an hour or so after meals and at bedtime and anticholinergic given at bedtime to selected patients are especially useful in management of peptic ulcer disease. More or less extensive schedules may be indicated, depending on the severity of disease and symptoms.
抗酸剂和抗胆碱能药物应被视为具有潜在严重副作用的强效药理学药物。在考虑了构成这些治疗方式主要禁忌症的情况并排除其存在后，由于胃酸和胃蛋白酶的作用，抗酸剂和抗胆碱能药物在控制疾病症状和病程方面是有用的。饭后约一小时及睡前服用抗酸剂，睡前给选定患者服用抗胆碱能药物，对消化性溃疡疾病的治疗特别有用。根据疾病和症状的严重程度，可能需要或多或少广泛的用药方案。
