Kwok Y K, Giam Y C, Tan S H, Sim C S
National Skin Centre, 1 Mandalay Road, Singapore 308205.
Ann Acad Med Singap. 2001 Jan;30(1):32-7.
A retrospective study of melanocytic naevi was undertaken to assess the degree of clinico-pathological correlation and incidence of histological atypia.
The case records from January to March 1996 of all patients with histologically diagnosed melanocytic naevi at the National Skin Centre were analysed.
Of the 240 lesions removed from 167 patients, the majority being women (111/167 patients), it was found that 55% (132/240) were correctly diagnosed. Fourteen per cent were mistaken for non-melanocytic lesions, namely skin tag, neurofibroma, syringoma cylindroma, epidermal naevus, naevus sebaceous and basal cell carcinoma. Most of the lesions were located on the cheeks and eyelids. Junctional naevi, followed by compound naevi were often missed. Histological dysplasia were seen in 7 naevi; 6 compound and 1 congenital naevi. There was a lack of clinico-pathological concordance in dysplastic naevi.
The clinico-pathological concordance of melanocytic naevi was high, with low incidence of atypia on histology.
开展了一项关于黑素细胞痣的回顾性研究，以评估临床病理相关性程度及组织学异型性的发生率。
分析了国立皮肤中心1996年1月至3月间所有经组织学诊断为黑素细胞痣患者的病例记录。
在从167例患者身上切除的240个皮损中，大多数为女性（111/167例患者），发现55%（132/240）被正确诊断。14%被误诊为非黑素细胞性皮损，即皮赘、神经纤维瘤、圆柱瘤型汗腺螺旋腺瘤、表皮痣、皮脂腺痣和基底细胞癌。大多数皮损位于脸颊和眼睑。交界痣，其次是复合痣，常被漏诊。7例痣可见组织学发育异常；6例复合痣和1例先天性痣。发育异常痣缺乏临床病理一致性。
黑素细胞痣的临床病理一致性较高，组织学异型性发生率较低。
