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[诊断性腹腔镜检查——腹部淋巴瘤的一种有用工具]

[Diagnostic laparoscopy--a useful tool in abdominal lymphoma].

作者信息

Lev-Chelouche D, Margal D, Klausner J M, Szold A

机构信息

Dept. of Surgery B, Tel Aviv-Sourasky Medical Center, Sackler Medical Faculty, Tel Aviv University.

出版信息

Harefuah. 2001 Feb;140(2):103-5, 191.

Abstract

Imaging-guided (CT/US) percutaneous biopsy has significantly improved diagnosis of intra-abdominal lymphoma. However, in many cases the tissue retrieved may be inadequate for specialized studies such as immunophenotyping or cytogenetic analysis that may be required for a complete analysis of lymphoma or determination of therapy. The success of diagnostic laparoscopy in the diagnosis and staging of gastrointestinal malignancies suggests that it could be used for intra-abdominal lymphomas as well. We describe our experience in 15 patients with suspected lymphoma who underwent diagnostic laparoscopy during 1995-98. Preoperative investigation performed in all included percutaneous FNA in 9 without conclusive diagnosis. Laparoscopy was diagnostic for lymphoma in 14 (93%) while in 1 there was a false negative result due to sampling error and the lymphoma was only diagnosed at a second laparoscopy. There was no mortality nor any major complication. Average hospital stay was 2 days and patients were then referred for further oncological treatment. Our experience shows that diagnostic laparoscopy is a safe and efficient tool and without major complications in diagnosing abdominal lymphoma.

摘要

影像引导下(CT/超声)经皮活检显著提高了腹内淋巴瘤的诊断水平。然而,在许多情况下,获取的组织可能不足以进行专门研究,如免疫表型分析或细胞遗传学分析,而这些分析对于淋巴瘤的全面分析或治疗方案的确定可能是必需的。诊断性腹腔镜检查在胃肠道恶性肿瘤的诊断和分期方面的成功表明,它也可用于腹内淋巴瘤。我们描述了1995年至1998年间15例疑似淋巴瘤患者接受诊断性腹腔镜检查的经验。所有患者术前均进行了检查,其中9例进行了经皮细针穿刺抽吸活检,但未得出明确诊断。14例(93%)患者经腹腔镜检查确诊为淋巴瘤,1例因取材误差出现假阴性结果,该例淋巴瘤仅在第二次腹腔镜检查时才得以确诊。无死亡病例,也未发生任何严重并发症。平均住院时间为2天,随后患者被转介接受进一步的肿瘤治疗。我们的经验表明,诊断性腹腔镜检查是一种安全有效的工具,在诊断腹部淋巴瘤时不会出现严重并发症。

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