Structure-activity relationships for antimicrobial cephalosporins.
作者信息
Tinland B
出版信息
Res Commun Chem Pathol Pharmacol. 1975 Jan;10(1):173-6.
PMID:1124313
Abstract
The antimicrobial activity of a series of 7-mandelamido-3-cephem-4-carboxylic acids was studied using the Free-Wilson method. Electron-withdrawing and lipophilic properties of the substituents are shown to play an important role in the activity.
摘要
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