Kim C J, Day S, Yeh K A
Department of Surgery, Medical College of Georgia, Augusta 30912, USA.
Am Surg. 2001 Feb;67(2):111-4.
Metastatic squamous cell carcinoma of the soft tissue is extremely rare. We report two patients with soft tissue metastasis from squamous cell carcinoma of the cervix in one and scalp in another. Case 1: A 63-year-old black woman with a history of cervical cancer presented with a painful mass over the right scapula. An incisional biopsy revealed squamous cell carcinoma. She underwent radiation treatment followed by wide local excision with en bloc resection and a myocutaneous flap closure. Case 2: A 46-year-old white man with a history of squamous cell carcinoma of the scalp and two kidney transplantations requiring long-term immunosuppression presented with a 2-month history of a left proximal arm mass. Magnetic resonance imaging revealed that the mass was within the triceps muscle and fixed to the humerus. Biopsy revealed squamous cell carcinoma. He underwent a shoulder disarticulation for tumor invasion into the adjacent humerus and neurovascular bundles. The patients remain disease-free at 12 and 8 months, respectively. To our knowledge there are no reports of soft tissue squamous cell carcinoma metastatic from the cervix and only rare cases from the lung, head, and neck. The optimal mode of treatment and prognosis is undefined in these patients because of its rare incidence. Surgery and radiation with curative intent were used.
软组织转移性鳞状细胞癌极为罕见。我们报告了两例患者，一例是宫颈鳞状细胞癌转移至软组织，另一例是头皮鳞状细胞癌转移至软组织。病例1：一名63岁的黑人女性，有宫颈癌病史，右肩胛处出现疼痛性肿块。切开活检显示为鳞状细胞癌。她接受了放射治疗，随后进行了广泛局部切除，包括整块切除和肌皮瓣闭合术。病例2：一名46岁的白人男性，有头皮鳞状细胞癌病史，因两次肾移植需要长期免疫抑制，出现左近端手臂肿块2个月。磁共振成像显示肿块位于肱三头肌内并与肱骨固定。活检显示为鳞状细胞癌。由于肿瘤侵犯相邻肱骨和神经血管束，他接受了肩关节离断术。这两名患者分别在12个月和8个月时仍无疾病复发。据我们所知，尚无宫颈鳞状细胞癌转移至软组织的报道，仅有罕见的肺、头颈部鳞状细胞癌转移至软组织的病例。由于其发病率低，这些患者的最佳治疗方式和预后尚不明确。我们采用了旨在治愈的手术和放疗方法。
