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肝血管瘤治疗的栓塞术

Embolization for management of hepatic hemangiomas.

作者信息

Deutsch G S, Yeh K A, Bates W B, Tannehill W B

机构信息

Department of Surgery, Medical College of Georgia, Augusta 30912, USA.

出版信息

Am Surg. 2001 Feb;67(2):159-64.

Abstract

Hemangiomas represent the most common primary tumor of the liver. Clinically the significance of these lesions is highly variable. The management of hemangiomas is controversial and is intimately related to the size, symptoms, and associated comorbidities of the patients who harbor these benign tumors. Series suggest that the vast majority of hemangiomas are less than 4 cm, asymptomatic, and clinically incidental findings. Symptomatic hemangiomas are large and associated with a constellation of vague upper abdominal complaints including pain, mass, distention, early satiety, and weight loss. A number of small series of surgically treated symptomatic hemangiomas have demonstrated enucleation as a safe and effective intervention. We report a collection of case reports using embolization as a primary treatment of symptomatic hemangiomas. The first patient is a 73-year-old black man previously treated for prostate cancer by radical prostatectomy and radiation. He developed weight loss, abdominal fullness, and early satiety. His symptoms were attributed to a large left lateral segmental liver mass that was biopsy proven to be a hemangioma. The second patient is a 49-year-old black women who complained of weakness, fatigue, night sweats, and anemia. The only abnormality discovered was a large right posterior hemangioma. The third patient is a 49-year-old black women with unexplained right upper quadrant pain and anemia who was found to have a 19 x 11 x 7.5-cm left hepatic hemangioma by CT. All three patients underwent elective treatment of their hemangiomas with highly selective hepatic embolization. There were no significant complications related to the procedures. Symptoms resolved for all patients acutely after treatment. The use of embolization for hepatic hemangiomas provides safe and effective treatment of the patient's symptoms while avoiding operative intervention, extended hospitalization, or postoperative recuperation. This treatment modality should be considered for the symptomatic hemangioma under elective conditions.

摘要

肝血管瘤是肝脏最常见的原发性肿瘤。临床上,这些病变的意义差异很大。肝血管瘤的治疗存在争议,并且与患有这些良性肿瘤患者的大小、症状及合并症密切相关。系列研究表明,绝大多数肝血管瘤小于4厘米,无症状,是临床偶然发现的。有症状的肝血管瘤较大,伴有一系列上腹部模糊不适症状,包括疼痛、肿块、腹胀、早饱及体重减轻。一些关于手术治疗有症状肝血管瘤的小系列研究已证明摘除术是一种安全有效的干预措施。我们报告一组病例报告,这些病例使用栓塞作为有症状肝血管瘤的主要治疗方法。首例患者是一名73岁黑人男性,此前因前列腺癌接受了根治性前列腺切除术和放疗。他出现体重减轻、腹部胀满和早饱。其症状归因于肝脏左外侧叶的一个大肿块,活检证实为肝血管瘤。第二例患者是一名49岁黑人女性,主诉虚弱、疲劳、盗汗和贫血。发现的唯一异常是一个大的右后肝血管瘤。第三例患者是一名49岁黑人女性,有不明原因的右上腹疼痛和贫血,CT检查发现其左肝有一个19×11×7.5厘米的肝血管瘤。所有三名患者均接受了高选择性肝栓塞对其肝血管瘤的择期治疗。未出现与手术相关的严重并发症。治疗后所有患者的症状均迅速缓解。对肝血管瘤使用栓塞可安全有效地治疗患者症状,同时避免手术干预、延长住院时间或术后恢复。在择期情况下,对于有症状的肝血管瘤应考虑这种治疗方式。

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