Sousa J, Sharma R R, Delmendo A, Pawar S J
Department of Neurosurgery, Khoula Hospital, Muscat, Sultanate Of Oman.
J Clin Neurosci. 2001 Mar;8(2):173-6. doi: 10.1054/jocn.2000.0754.
Adenoid cystic carcinoma is a rare neoplasm arising from the exocrine glands such as salivary glands, lachrymal glands, upper respiratory tract, breast or uterine cervix. Intracranial involvement is commonly from direct skull base involvement, although metastasis may rarely be seen. The predisposition of the adenoid cystic carcinoma for perineural and perivascular invasion is the prime reason for the locally invasive character of the tumour, often extending into the cranium via foramina at the skull base. The authors report a case of primary orbito-cranial extradural adenoid cystic carcinoma and cranial metastasis away from the primary site. This patient initially had a local excision, and later an exenteration of the right eye followed by with radiotherapy. Within months she presented with an extradural cranial recurrence, distant torcular metastasis without any neurological deficit. Craniotomy and radical excision was undertaken as these tumours have slow growth rates, and long term survival of the se patients even in the presence of local recurrence and metastasis has been well documented.
腺样囊性癌是一种罕见的肿瘤，起源于外分泌腺，如唾液腺、泪腺、上呼吸道、乳腺或子宫颈。颅内受累通常是由于直接侵犯颅底，不过很少见转移。腺样囊性癌易于沿神经和血管周围浸润，这是该肿瘤具有局部侵袭性的主要原因，常通过颅底的孔道延伸至颅内。作者报告了一例原发性眶-颅硬膜外腺样囊性癌并伴有远离原发部位的颅转移病例。该患者最初接受了局部切除，随后进行了右眼摘除术并辅以放疗。数月后，她出现了硬膜外颅复发、远处窦汇转移，但无任何神经功能缺损。由于这些肿瘤生长缓慢，因此进行了开颅根治性切除，而且即便存在局部复发和转移，这些患者的长期生存情况也已有充分记录。
