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[脑膜炎球菌血症、复发、诊断与治疗]

[Meningococcemia, recrudescence, diagnosis and treatment].

作者信息

Tomat A M, Trippaerts M, Senterre J, Lequarré F, De Mol P

机构信息

Département Universitaire de Pédiatrie du CHR Citadelle.

出版信息

Rev Med Liege. 2000 Oct;55(10):915-20.

Abstract

Meningococcemia is a severe Gram negative septicemia whose mortality may be as high as 30%. It occurs more frequently in children but the proportion of teenagers is increasing in Belgium. During the past decade, a slow but sustained rise in the incidence of this illness has been noted, with a predominance of the serogroup B. We describe the symptoms, which often are poor in the early stage, the different therapies, most of them being still under investigation, and the chemoprophylaxis. Without being alarmist, the diagnosis must be considered in any child with cutaneous rash, even atypical and tachycardia.

摘要

脑膜炎球菌血症是一种严重的革兰氏阴性败血症,其死亡率可能高达30%。它在儿童中更常见,但在比利时青少年中的比例正在上升。在过去十年中,已注意到这种疾病的发病率缓慢但持续上升,以B血清群为主。我们描述了其症状(早期通常不明显)、不同的治疗方法(其中大多数仍在研究中)以及化学预防措施。在不危言耸听的情况下,对于任何有皮疹(即使是非典型皮疹)和心动过速的儿童都必须考虑进行诊断。

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