Seides S F, DeJoseph R L, Brown A E, Damato A N
Am J Cardiol. 1975 May;35(5):679-82. doi: 10.1016/0002-9149(75)90056-9.
The effects of surgically created tricuspid insufficiency on the right ventricular dimension and the motion of the interventricular septum were determined by serial echocardiography in a patient with a hemodynamically normal heart who underwent tricuspid valvulectomy and later tricuspid valve replacement for medically intractable bacterial endocarditis. Initially, both the right ventricular dimension (1.8 cm) and motion of the interventricular septum were normal. After valvulectomy interventricular septal motion became distinctly paradoxical (pattern A, later pattern B), and the right ventricular dimension progressively increased to 3.5 cm. After successful tricuspid valve replacement interventricular septal motion promptly returned toward normal as did the right ventricular dimension (2.2 cm). The rapid changes in these echocardiographic variables with creation and relief of acute right ventricular volume overload correspond well with results of previous work in experimental animals but differ from findings in man with chronic right ventricular volume overload.
通过连续超声心动图检查，在一名血流动力学正常的心脏患者中，确定了手术造成的三尖瓣关闭不全对右心室大小和室间隔运动的影响。该患者因药物治疗无效的细菌性心内膜炎接受了三尖瓣切除术，随后进行了三尖瓣置换术。最初，右心室大小（1.8厘米）和室间隔运动均正常。瓣膜切除术后，室间隔运动变得明显反常（最初为A型，后来为B型），右心室大小逐渐增加至3.5厘米。成功进行三尖瓣置换术后，室间隔运动迅速恢复正常，右心室大小也恢复正常（2.2厘米）。这些超声心动图变量随急性右心室容量超负荷的产生和缓解而迅速变化，与先前在实验动物中的研究结果非常吻合，但与慢性右心室容量超负荷患者的研究结果不同。
