意大利小细胞血症筛查：过去30年收集数据的分析
Screening for microcytemia in Italy: analysis of data collected in the past 30 years.
作者信息
Silvestroni E, Bianco I
出版信息
Am J Hum Genet. 1975 Mar;27(2):198-212.
Abstract
Extensive population surveys begun in Italy in 1943 revealed a high incidence of mycrocytemia. Health authorities established a national organization to combat microcytemia which financed and directed activities throughout Italy from 1955 to 1971. The work performed by the microcytemia centers in screening and prophylaxis is described. The results of a screening program underway since 1967 involving 46,559 students of the University of Rome are presented in detail. A preliminary survey of 256 families revealed that the incidence of subsequent births after the births of a child affected by Cooley's anemia was generally low. Results obtained to date are encouraging and justify more extensive programs for the prevention and treatment of microcytemia.
摘要
1943年在意大利开始的广泛人口调查显示小细胞血症发病率很高。卫生当局成立了一个全国性组织来对抗小细胞血症，该组织在1955年至1971年期间为意大利各地的活动提供资金并进行指导。描述了小细胞血症中心在筛查和预防方面所开展的工作。详细介绍了自1967年以来对罗马大学46,559名学生进行的一项筛查项目的结果。对256个家庭的初步调查显示，受库利贫血影响的孩子出生后，后续出生的孩子发病率普遍较低。迄今为止获得的结果令人鼓舞，为开展更广泛的小细胞血症防治项目提供了依据。
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