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意大利、西班牙和土耳其的血红蛋白病移民和筛查计划。

Immigration and screening programs for hemoglobinopathies in Italy, Spain and Turkey.

机构信息

Thalassemia Diagnosis Center of Mediterranean Blood Diseases Foundation, Antalya (Turkey).

Red Blood Cell and Haematopoietic Disorders Unit, Institute for Leukemia Research Josep Carreras (IJC) and University of Barcelona, Catalonia (Spain).

出版信息

Acta Biomed. 2021 Sep 2;92(4):e2021410. doi: 10.23750/abm.v92i4.11965.

DOI:10.23750/abm.v92i4.11965
PMID:34487057
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8477095/
Abstract

Sickle cell disease (SCD) and thalassemias are the most common monogenic diseases in the world. The number of migrants and refugees in Europe and Turkey, in the past decade, has increased dramatically due to war, violence or prosecutions in their homeland. Prevention and management of haemoglobin disorders is well established and managed in countries where these conditions were traditionally endemic or in countries that have a longstanding tradition of receiving migrants. Therefore, preventive and diagnostic programmes regarding hemoglobinopathies in immigrant populations have been implemented. The purpose of this paper it to report a summary of the experience gained in Italy, Spain and Turkey in migrants, asylum seekers and refugees.

摘要

镰状细胞病(SCD)和地中海贫血症是世界上最常见的单基因疾病。由于战争、暴力或在原籍国受到起诉,过去十年来,欧洲和土耳其的移民和难民人数急剧增加。在这些疾病传统流行的国家或在长期接收移民的国家,血红蛋白疾病的预防和管理已经得到很好的确立和管理。因此,已经针对移民人群中的血红蛋白病实施了预防和诊断计划。本文的目的是报告意大利、西班牙和土耳其在移民、寻求庇护者和难民方面所获得经验的总结。

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Acta Biomed. 2021 Sep 2;92(4):e2021410. doi: 10.23750/abm.v92i4.11965.
2
Refugee movements and Turkey.难民流动与土耳其。
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本文引用的文献

1
The Prevention of Thalassemia Revisited: A Historical and Ethical Perspective by the Thalassemia International Federation.《重新审视地中海贫血症的预防:地中海贫血国际联合会的历史和伦理视角》。
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Newborn Screening for Sickle Cell Disease in Europe.欧洲镰状细胞病的新生儿筛查
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Update of the Spanish registry of haemoglobinopathies in children and adults.西班牙儿童和成人血红蛋白病登记处的更新情况。
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Orphanet J Rare Dis. 2019 May 30;14(1):120. doi: 10.1186/s13023-019-1099-0.
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Access to emergency departments for acute events and identification of sickle cell disease in refugees.难民急性事件的急诊科就诊情况及镰状细胞病的识别
Blood. 2019 May 9;133(19):2100-2103. doi: 10.1182/blood-2018-09-876508. Epub 2019 Feb 11.
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Refugee children with beta-thalassemia in Turkey: Overview of demographic, socioeconomic, and medical characteristics.土耳其患有β-地中海贫血症的难民儿童:人口统计学、社会经济学和医学特征概述。
Pediatr Blood Cancer. 2019 May;66(5):e27636. doi: 10.1002/pbc.27636. Epub 2019 Feb 1.
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The current state of sickle cell trait: implications for reproductive and genetic counseling.镰状细胞特征的现状:对生殖和遗传咨询的影响。
Blood. 2018 Nov 29;132(22):2331-2338. doi: 10.1182/blood-2018-06-848705.
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Newborn screening for sickle cell disease in Europe: recommendations from a Pan-European Consensus Conference.欧洲新生儿镰状细胞病筛查:泛欧共识会议的建议。
Br J Haematol. 2018 Nov;183(4):648-660. doi: 10.1111/bjh.15600. Epub 2018 Oct 18.
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Universal Screening Program in Pregnant Women and Newborns at-Risk for Sickle Cell Disease: First Report from Northern Italy.针对镰状细胞病高危孕妇和新生儿的普遍筛查项目:来自意大利北部的首份报告。
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European migration crises: The role of national hemoglobinopathy registries in improving patient access to care.欧洲移民危机:国家血红蛋白病登记处对改善患者医疗服务可及性的作用。
Pediatr Blood Cancer. 2017 Jul;64(7). doi: 10.1002/pbc.26515. Epub 2017 Mar 30.