触珠蛋白与ABO血型的相互作用：对ABO血型不相容交配后代中触珠蛋白1过量现象的一种可能解释。
Haptoglobin-ABO interaction: a possible explanation for the excess of Hp 1 among offspring of ABO incompatible matings.
作者信息
Vana L R, Steinberg A G
出版信息
Am J Hum Genet. 1975 Mar;27(2):224-32.
The Hp1 frequency among ABO phenotypes varies in the Hutterite population as follows: O less than A less than B less than AB. Within group O, the Hp1 frequency is significantly lower than the Hp1 frequency among the other groups combined. The Hp1 frequencies among ABO genotypes, known by means of family pedigrees, vary as follows: OO less than AO less than BO less than AB less than AA less than BB. This holds for both main subjects of this isolate, although they have been reproductively isolated since World War I. The higher Hp1 frequency among type A, B, and AB individuals explains the observation of the higher Hp1 frequencies found among H-leut offspring who are incompatible with their mothers (mainly AO offspring of OO mothers) compared to offspring from the same matings who are compatible with their mothers.
在哈特派人群中，ABO血型表型中的Hp1频率变化如下：O型低于A型低于B型低于AB型。在O型组中，Hp1频率显著低于其他组合并后的Hp1频率。通过家系得知的ABO基因型中的Hp1频率变化如下：OO型低于AO型低于BO型低于AB型低于AA型低于BB型。这在该隔离群体的两个主要群体中均成立，尽管自第一次世界大战以来他们在生殖上已被隔离。A、B和AB型个体中较高的Hp1频率解释了这样一个观察结果，即与母亲血型不相容的H-路德后代（主要是OO型母亲的AO型后代）中发现的Hp1频率高于与其母亲血型相容的相同交配后代中的Hp1频率。
Zotero 插件