酶增强减敏作用：IV. 鱼精蛋白对小鼠及花粉症患者β-葡萄糖醛酸酶免疫行为的影响
Enzyme potentiated hyposensitization: IV. effect of protamine on the immunological behavior of beta glucuronidase in mice and patients with hay fever.
作者信息
McEwen L M, Nicholson M, Kitchen I, O'Gorman J, White S
出版信息
Ann Allergy. 1975 May;34(5):290-5.
PMID:1124865
Abstract
The ability of beta glucuronidase and a small dose of antigen to modify the anaphylactic reaction of previously sensitized mice has been further investigated. Protamine has an important effect on the immunological behavior of the enzyme. A trial on hay fever patients shows that the results in mice are relevant and that the method can produce significant clinical hyposensitization.
摘要
已进一步研究了β-葡萄糖醛酸酶和小剂量抗原改变先前致敏小鼠过敏反应的能力。鱼精蛋白对该酶的免疫行为有重要影响。一项针对花粉热患者的试验表明，小鼠实验结果具有相关性，且该方法可产生显著的临床减敏作用。
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