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抗结核病的DNA疫苗。

DNA vaccines against tuberculosis.

作者信息

Lowrie D B

机构信息

National Institute for Medical Research, Ridgeway, Mill Hill, London, NW7 1AA, UK.

出版信息

Curr Opin Mol Ther. 1999 Feb;1(1):30-3.

Abstract

Application of the DNA vaccine approach to tuberculosis in laboratory animals is helping to clarify the immunological mechanisms underlying protective immunity. Unexpectedly, it has also indicated clear potential for clinical application. This review looks at the implication of recent advances for the development of practical TB vaccines.

摘要

在实验动物中将DNA疫苗方法应用于结核病,有助于阐明保护性免疫背后的免疫机制。出乎意料的是,这也显示出了明确的临床应用潜力。本综述探讨了近期进展对实用结核病疫苗开发的意义。

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