1964 - 1970年尼日利亚的虫媒病毒感染人类情况

Arthropod-borne viral infections of man in Nigeria, 1964-1970.

作者信息

Moore D L, Causey O R, Carey D E, Reddy S, Cooke A R, Akinkugbe F M, David-West T S, Kemp G E

出版信息

Ann Trop Med Parasitol. 1975 Mar;69(1):49-64. doi: 10.1080/00034983.1975.11686983.

DOI:10.1080/00034983.1975.11686983

Abstract

During the years 1964 to 1970, 171 arboviruses of 15 different types were isolated from humans in Nigeria. Isolation rates were highest in 1969, and lowest in 1965 and 1967. Monthly arbovirus activity was highest in the rainy season months of June, July and August and lowest in the dry months of January and February. Viruses were isolated from all age groups, with the majority from children one to four years old. The viruses isolated in largest numbers were chikungunya and yellow fever, which caused epidemics in 1969, and dengue types 1 and 2 and Tataguine, which are endemic in Ibadan. Bwamba virus was isolated in 1964 and 1969, and Bunyamwera group viruses were encountered for the first time in 1969. Other viruses recovered less frequently were Zika, Igbo-Ora (an agent related to o'nyong-nyong), two viruses related to the Uganda mosquito virus Ug MP 359, Dugbe, Thogoto, Lebombo and Shuni. Several of these are new agents and have not previously been isolated from man. Clinical details are presented where available.

摘要

1964年至1970年间，在尼日利亚从人体中分离出15种不同类型的171种虫媒病毒。分离率在1969年最高，在1965年和1967年最低。虫媒病毒的月度活动在6月、7月和8月的雨季月份最高，在1月和2月的旱季月份最低。病毒从所有年龄组中分离出来，大多数来自1至4岁的儿童。分离出数量最多的病毒是基孔肯雅病毒和黄热病毒，它们在1969年引发了疫情，还有1型和2型登革病毒以及塔塔圭纳病毒，这些病毒在伊巴丹是地方性流行病毒。布万巴病毒在1964年和1969年被分离出来，布尼亚姆韦拉病毒组在1969年首次被发现。其他较少分离到的病毒有寨卡病毒、伊博奥拉病毒（一种与奥尼昂尼昂病毒相关的病原体）、两种与乌干达蚊病毒Ug MP 359相关的病毒、杜格贝病毒、托戈托病毒、莱邦博病毒和舒尼病毒。其中几种是新病原体，以前未曾从人体中分离出来。如有可用的临床细节也一并列出。