[血管生成的影像学]

[Imaging of angiogenesis].

作者信息

Bremer C, Bogdanov A A, Weissleder R

机构信息

Center for Molecular Imaging Research, Massachusetts General Hospital and Harvard Medical School, Boston, USA.

出版信息

Radiologe. 2001 Feb;41(2):138-45. doi: 10.1007/s001170050956.

DOI:10.1007/s001170050956

PMID:11253099

Abstract

Angiogenesis of tumors has gained tremendous attention in the research community over the last years. Novel anti-angiogenic treatment protocols are currently in various phases of clinical testing. Thus, the major challenge for Radiological diagnostics is to develop imaging methods which reliably measure the angiogenic tumor burden as well as tumor response to anti-angiogenic treatment in vivo. This article intends to provide a brief overview of imaging strategies for angiogenesis and anti-angiogenic treatment.

摘要

在过去几年中，肿瘤血管生成在研究领域受到了极大关注。新型抗血管生成治疗方案目前正处于不同阶段的临床试验中。因此，放射诊断学面临的主要挑战是开发能够在体内可靠测量肿瘤血管生成负担以及肿瘤对抗血管生成治疗反应的成像方法。本文旨在简要概述血管生成及抗血管生成治疗的成像策略。