Chemaly D, Lefrançois A, Pérusse R
Toronto General Hospital.
J Can Dent Assoc. 2000 Dec;66(11):600-5.
Multiple sclerosis is a chronic demyelinating disease of the central nervous system which mostly affects young adults living in the northern hemisphere. It is a disease primarily found in temperate climates, being rare in the tropics and increasing in frequency with distance from the equator. Canada has one of the highest prevalence rates in the world. Dentists should be familiar with the clinical manifestations that affect the oral and maxillofacial areas as well as patients' general health. Three of the most frequent oro-facial symptoms include trigeminal neuralgia, trigeminal sensory neuropathy and facial palsy. Dentists should also be aware of the importance of this disease in the diagnosis, treatment and prognosis of certain oro-facial lesions or conditions. This paper reviews 2 cases of multiple sclerosis, highlights its oro-facial manifestations and discusses the dental implications of the disease.
多发性硬化症是一种中枢神经系统的慢性脱髓鞘疾病,主要影响生活在北半球的年轻人。这是一种主要在温带气候地区发现的疾病,在热带地区罕见,且随着与赤道距离的增加发病率上升。加拿大是世界上患病率最高的国家之一。牙医应熟悉影响口腔颌面部区域的临床表现以及患者的整体健康状况。三种最常见的口腔面部症状包括三叉神经痛、三叉神经感觉神经病变和面瘫。牙医还应意识到这种疾病在某些口腔面部病变或病症的诊断、治疗和预后中的重要性。本文回顾了2例多发性硬化症病例,突出了其口腔面部表现,并讨论了该疾病对牙科的影响。