Glosemeyer R, Deppe H, Dormann A J, Wigginghaus B, Stolte M, Stadler R, Huchzermeyer H
Medizinische Klinik, Klinikum Bayreuth.
Z Gastroenterol. 2001 Feb;39(2):167-71. doi: 10.1055/s-2001-11148.
We report the case of a 39-year-old German women who suffered from chronic inflammatory bowel disease which had not been exactly classified for 6 years. In the course of the disease she developed recurrent iritis, nodular skleritis, oral and genital ulcer, erythema nodosum and axillary folliculitis. For the first time retrosternal pain occurred. Endoscopy of the upper gastrointestinal tract showed mid esophageal ulcer formation. Colonoscopy demonstrated ulcerative colitis with no involvement of rectal mucosa. Histologically a cutaneous vasculitis in the lower limb was seen and diagnosis of Adamantiades-Behçet disease with marked gastrointestinal involvement and rare manifestation in the esophagus was established. A therapy with prednisolone, azathioprine and mesalazine was started. Under this regimen stomatitis, esophagitis and cutaneous vasculitis resolved, while the colitis showed partial remission now for up to one year.
我们报告了一例39岁的德国女性病例，她患有慢性炎症性肠病，6年来一直未得到确切分类。在疾病过程中，她出现了复发性虹膜炎、结节性巩膜炎、口腔和生殖器溃疡、结节性红斑和腋窝毛囊炎。首次出现胸骨后疼痛。上消化道内镜检查显示食管中段溃疡形成。结肠镜检查显示溃疡性结肠炎，直肠黏膜未受累。组织学检查发现下肢有皮肤血管炎，确诊为白塞病，伴有明显的胃肠道受累且食管表现罕见。开始使用泼尼松龙、硫唑嘌呤和美沙拉嗪进行治疗。在这种治疗方案下，口腔炎、食管炎和皮肤血管炎得到缓解，而结肠炎目前部分缓解已达一年。
