Kisel M A, Kuchuro S V, Litvinko N M
Institute of Bioorganic Chemistry, National Academy of Sciences of Belarus, Minsk, 220141, Belarus.
Biochemistry (Mosc). 2001 Feb;66(2):168-72. doi: 10.1023/a:1002839514279.
Hydrolysis of dioleoylphosphatidylethanol (DOPEt) and dioleoylphosphatidylcholine (DOPC) catalyzed by phospholipase A2 (PLA2) from porcine pancreas has been studied in single-component and binary liposomes in the absence and in the presence of ethanol. DOPEt (an anionic phospholipid) was found to increase the rate of hydrolysis of zwitterionic DOPC in liposomes under the action of PLA2.
研究了猪胰腺磷脂酶A2（PLA2）催化的二油酰磷脂酰乙醇（DOPEt）和二油酰磷脂酰胆碱（DOPC）在单组分和二元脂质体中，在不存在和存在乙醇的情况下的水解情况。发现DOPEt（一种阴离子磷脂）在PLA2的作用下会提高脂质体中两性离子DOPC的水解速率。
