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[五种植物油对大鼠血脂及脂质过氧化的影响]

[Effect of five kinds of vegetable seed oil on serum lipid and lipid peroxidation in rats].

作者信息

Guo Y, Cai X, Zhao X, Shi R

机构信息

School of Preventive Medicine, Norman Bethune University of Medical Sciences, Changchun 130021, China.

出版信息

Wei Sheng Yan Jiu. 2001 Jan;30(1):50-1.

Abstract

The effects of vegetable seed oil on hyperlipidemia induced by high lipid diet in rats. Male adult Wistar rats were fed on the test diet containing 94% high lipid diet and 6% lard pinon seed oil, perilla seed oil, blackcurrent seed oil, borage seed oil and evening primrose seed oil respectively for 3 weeks. The results showed that the vale of trilyceride(TG), total cholesterol(TC), low density lipoprotein cholesterol (LDL-C), LDL-C/HDL-C(high density lipoprotein cholesterol) ratio increased and the vale of HDL-C/TC ratio and lecithin-cholesterol acyltransferase(LCAT) activity decreased in the groups with vegetable seed oil were less than that of the control group. The results suggested that all the five kinds of vegetable seed oil had the effect of regulating lipid metabolism of hyperlipidemia rats to some extent. Pinon seed oil and borage seed oil may be well suited for the prevention of atherosclerosis.

摘要

植物油对高脂饮食诱导的大鼠高脂血症的影响。雄性成年Wistar大鼠分别喂食含94%高脂饮食和6%猪油、松子籽油、紫苏籽油、黑加仑籽油、琉璃苣籽油和月见草油的试验饮食3周。结果显示,与对照组相比,添加植物油组的甘油三酯(TG)、总胆固醇(TC)、低密度脂蛋白胆固醇(LDL-C)、LDL-C/高密度脂蛋白胆固醇(HDL-C)比值升高,HDL-C/TC比值和卵磷脂胆固醇酰基转移酶(LCAT)活性降低。结果表明,这五种植物油在一定程度上均有调节高脂血症大鼠脂质代谢的作用。松子籽油和琉璃苣籽油可能非常适合预防动脉粥样硬化。

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