Alexandersen O
Lungeseksjonen Medisinsk avdeling Nordland sentralsykehus 8092 Bodø.
Tidsskr Nor Laegeforen. 2001 Feb 10;121(4):407-9.
The aim of this study was to examine our lung cancer patients, particularly their smoking habits and survival rates.
Information was recorded prospectively on 219 patients seen in our hospital from 1987 to 1992.
Average age was 65.5 years (39-85 years). 27% were female. 9% were 49 years or younger, 13 men and seven women. Only six patient (3%) were non-smokers, 77% were smokers and 20% ex-smokers. 52 patients (24%) had small cell lung cancer (SCLC) and 167 (76%) non-small cell lung cancer (NSCLC). All six non-smokers had adenocarcinoma (two bronchioloalveolar cell carcinoma). 63% had advanced disease (stage IIIB and IV or small cell cancer, extensive disease). Only 22 patients (10%) were alive at five years: 19 patients with NSCLC who had got surgical treatment, one patient with NSCLC (stage IIIB) who had recieved radiotherapy, and two patients with SCLC, limited disease, treated with chemo- and radiotherapy. The surgically treated patients (23%) had a five-year survival of 50% (17/33) at stage I, 33% (2/6) at stage II, and none (0/7) at stage IIIA.
This poor outlook for patients with lung cancer and the fact that there are few non-smokers among them, tell us that the major emphasis must be on prevention.
本研究旨在对肺癌患者进行调查，尤其是了解他们的吸烟习惯和生存率。
前瞻性记录了1987年至1992年在我院就诊的219例患者的信息。
平均年龄为65.5岁（39 - 85岁）。女性占27%。9%的患者年龄在49岁及以下，其中男性13例，女性7例。只有6例患者（3%）不吸烟，77%为吸烟者，20%为曾经吸烟者。52例患者（24%）患有小细胞肺癌（SCLC），167例（76%）患有非小细胞肺癌（NSCLC）。所有6例不吸烟者均为腺癌（2例细支气管肺泡癌）。63%的患者患有晚期疾病（IIIB期和IV期或小细胞癌广泛期）。仅22例患者（10%）在5年后仍存活：19例接受手术治疗的NSCLC患者，1例接受放疗的NSCLC患者（IIIB期），以及2例患有局限性疾病的SCLC患者，接受了化疗和放疗。接受手术治疗的患者中，I期患者5年生存率为50%（17/33），II期患者为33%（2/6），IIIA期患者无存活（0/7）。
肺癌患者预后不佳，且其中非吸烟者较少，这表明必须将重点主要放在预防上。
