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患自闭症的儿童在接种麻腮风疫苗后会更频繁地就诊吗?

Do children who become autistic consult more often after MMR vaccination?

作者信息

DeWilde S, Carey I M, Richards N, Hilton S R, Cook D G

机构信息

Department of General Practice and Primary Care, George's Hospital Medical School, London SW17 0RE.

出版信息

Br J Gen Pract. 2001 Mar;51(464):226-7.

Abstract

A close temporal association has been reported between the measles, mumps, and rubella (MMR) vaccination and dramatic behavioural decline in children subsequently diagnosed as autistic. We hypothesised that such a decline would be reflected in increased consultations with the child's general practitioner. The Doctor's Independent Network database was used to examine whether children subsequently diagnosed as autistic consulted more frequently than controls after MMR vaccination. No difference in consulting behaviour was seen in the six months post MMR. Any dramatic effect of MMR on behaviour seems unlikely.

摘要

据报道,麻疹、腮腺炎和风疹(MMR)疫苗接种与随后被诊断为自闭症的儿童行为急剧下降之间存在密切的时间关联。我们假设这种下降会反映在儿童向全科医生咨询的次数增加上。利用医生独立网络数据库来检查随后被诊断为自闭症的儿童在接种MMR疫苗后咨询次数是否比对照组更频繁。在接种MMR疫苗后的六个月内,未发现咨询行为有差异。MMR疫苗对行为的任何显著影响似乎不太可能。

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