Ud-Din N, Mushtaq S, Mamoon N, Khan A H, Malik I A
Department of Histopathology and Morbid Anatomy, Armed Forces Institute of Pathology, Rawalpindi.
J Pak Med Assoc. 2001 Jan;51(1):19-22.
The objective of the study was to assess the frequency and pattern of ophthalmic tumours in Northern Pakistan.
This study included all ophthalmic tumours diagnosed during a one year period (January to December 1992).
One hundred and fourteen ophthalmic tumours were diagnosed at the Armed Forces Institute of Pathology (AFIP) and Pathology Department of the Army Medical College (AMC), Rawalpindi. Of these tumours, 70 were malignant (61.5%) and 44 were benign (38.5%). The age distribution of malignant ophthalmic tumours had two peaks. The first was seen in the paediatric age group and was mainly due to retinoblastoma. The second peak was seen above 50 years of age and was mainly due to conjunctival squamous cell carcinoma and malignant eyelid tumours which constituted 85% of the malignant ophthalmic tumours in paediatric age group. The average age at presentation of retinoblastoma was 3.8 years. The average age at presentation for squamous cell carcinoma was 56 years. Basal cell carcinoma was the most common malignant eyelid tumour (55%). The most common extraocular malignant orbital tumour was non-Hodgkin's lymphoma. Malignant melanoma of the uvea formed 22% of all melanomas diagnosed during this period. The most common benign tumours were naevi (33%), epidermal inclusion cysts (18%), choristomata (16%) and haemangioma (8%). The malignant ophthalmic tumours constituted 3% of all the malignant tumours diagnosed in Northern Pakistan during 1992 at AFIP and AMC, Rawalpindi.
The ophthalmic tumours, both benign and malignant are not infrequent in clinical practice in Northern Pakistan.
本研究的目的是评估巴基斯坦北部眼科肿瘤的发病率及模式。
本研究纳入了在一年期间（1992年1月至12月）诊断的所有眼科肿瘤。
在拉瓦尔品第的武装部队病理研究所（AFIP）和陆军医学院（AMC）病理科共诊断出114例眼科肿瘤。其中，70例为恶性（61.5%），44例为良性（38.5%）。恶性眼科肿瘤的年龄分布有两个高峰。第一个高峰出现在儿童年龄组，主要是由于视网膜母细胞瘤。第二个高峰出现在50岁以上，主要是由于结膜鳞状细胞癌和恶性眼睑肿瘤，它们占儿童年龄组恶性眼科肿瘤的85%。视网膜母细胞瘤的平均发病年龄为3.8岁。鳞状细胞癌的平均发病年龄为56岁。基底细胞癌是最常见的恶性眼睑肿瘤（55%）。最常见的眼外恶性眼眶肿瘤是非霍奇金淋巴瘤。葡萄膜恶性黑色素瘤占同期诊断的所有黑色素瘤的22%。最常见的良性肿瘤是痣（33%）、表皮样囊肿（18%）、迷离瘤（16%）和血管瘤（8%）。1992年在拉瓦尔品第的AFIP和AMC，恶性眼科肿瘤占巴基斯坦北部诊断的所有恶性肿瘤的3%。
在巴基斯坦北部的临床实践中，良性和恶性眼科肿瘤并不罕见。
