Judson R, Stephens J C
Genaissance Pharmaceuticals, 5 Science Park, New Haven, CT 06511, USA.
Pharmacogenomics. 2001 Feb;2(1):7-10. doi: 10.1517/14622416.2.1.7.
Single nucleotide polymorphisms (SNPs) and haplotypes are commonly used genetic markers in clinical studies. We provide some broad guidelines for deciding which of the two is most appropriate in particular circumstances. Molecular haplotyping techniques are also briefly reviewed and contrasted with electronic approaches.
单核苷酸多态性（SNPs）和单倍型是临床研究中常用的遗传标记。我们提供了一些宽泛的指导原则，以决定在特定情况下哪种标记最为合适。同时，我们还简要回顾了分子单倍型分型技术，并将其与电子方法进行了对比。
