Kragelund C B, Søndergaard L, Bjerrum O W
H:S Rigshospitalet, Hjertecentret, medicinsk kardiologisk afdeling B, og Finsencentret, medicinsk haematologisk afdeling L.
Ugeskr Laeger. 2001 Feb 26;163(9):1289-91.
Primary cardiac non-Hodgkin lymphoma is very rare. Results recently published suggest that the prognosis is good, if the lymphoma is diagnosed early. The symptoms are nevertheless unspecific and a clinical investigation is often inconclusive. We report a case of a woman with symptoms of severe dyspnoea at rest, chest pain, and fatigue. The ECG showed a complete atrioventricular block. Magnetic resonance imaging (MRI) revealed a tumour in the right atrium and ventricle. A myocardial biopsy showed malignant non-Hodgkin lymphoma of the diffuse, large cell B-type. The patient was treated with chemotherapy and control MRI after four treatments showed complete regression of the tumour.
原发性心脏非霍奇金淋巴瘤非常罕见。最近发表的结果表明,如果淋巴瘤能早期诊断,预后良好。然而,症状不具特异性,临床检查往往无定论。我们报告一例女性病例,该患者有静息时严重呼吸困难、胸痛和疲劳症状。心电图显示完全性房室传导阻滞。磁共振成像(MRI)显示右心房和右心室有肿瘤。心肌活检显示为弥漫性大细胞B型恶性非霍奇金淋巴瘤。患者接受了化疗,四次治疗后MRI复查显示肿瘤完全消退。