Rehm H L, Morton C C
Department of Genetics, Harvard Medical School, Boston, Massachusetts, USA.
Genet Med. 1999 Sep-Oct;1(6):295-302; quiz 303. doi: 10.1097/00125817-199909000-00009.
Recent advancements have been made in understanding, diagnosing, and treating deafness. In particular, much has been learned from the discovery of a small fraction of the genes responsible for deafness. This understanding will doubtless increase as additional genes are cloned and their functions elucidated. Trailing close behind these achievements will be more clinical advancements facilitating diagnosis of the etiologies of deafness. Integrating these genetic and clinical perspectives is critical to the development of better treatments and interventional strategies for deafness and its associated difficulties. Although opinions toward these advancements are likely to vary between the hearing population and the Deaf community, a growing understanding of the hearing process and how genetic variations result in deafness is ultimately likely to offer benefits to both groups.
在耳聋的理解、诊断和治疗方面取得了最新进展。特别是，通过发现一小部分导致耳聋的基因，我们学到了很多东西。随着更多基因被克隆并阐明其功能，这种理解无疑会增加。紧随这些成就之后的将是更多有助于诊断耳聋病因的临床进展。整合这些基因和临床观点对于开发更好的耳聋治疗方法和干预策略及其相关难题至关重要。尽管听力正常人群和聋人社区对这些进展的看法可能存在差异，但对听力过程以及基因变异如何导致耳聋的日益了解最终可能会给这两个群体都带来益处。
