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自膨式金属支架治疗胃窦幽门和/或十二指肠狭窄

Self-expandable metal stents in the treatment of antro-pyloric and/or duodenal strictures.

作者信息

Profili S, Meloni G B, Bifulco V, Conti M, Feo C F, Canalis G C

机构信息

Department of Radiology, University of Sassari, Sassari, Italy.

出版信息

Acta Radiol. 2001 Mar;42(2):176-80. doi: 10.1080/028418501127346477.

Abstract

PURPOSE

To assess the usefulness of self-expandable metal stents in the recanalization of antro-pyloric and/or duodenal strictures.

MATERIAL AND METHODS

We report our experience of 15 patients with inoperable antro-pyloric and/or duodenal strictures treated by implantation of 21 self-expandable metal stents (18 uncovered and 3 covered) inserted perorally under fluoroscopic guidance. The patients were 11 men and 4 women, mean age 65.3 years. Fourteen of 15 patients were affected by a malignant stricture of the antro-pyloric region and/or duodenum either primary or secondary in 10 and 4 cases, respectively. Only in 1 case there was a benign stricture from postoperative scarring. Stricture length and diameter varied from 3 to 9 cm (mean 5.4 cm) and from 0 to 4 mm (mean 1.27 mm), respectively.

RESULTS

Twenty-one stents were placed in 15 patients: Technical success was achieved in all cases while clinical improvement was obtained in 14 cases. No short-term complications were observed. A mean 4.3-month follow-up was obtained. Two patients had emesis secondary to peritoneal dissemination of the tumor after 1 and 2 months, respectively. Two other patients showed tumor overgrowth of the oral edge of the prosthesis after 3 and 2 months, respectively, and required another coaxial stent to bridge the new stenosis. The patient treated for a benign stricture had jaundice after 3 months and percutaneous internal-external biliary drainage was necessary.

CONCLUSION

Self-expandable metal stents are a safe and effective treatment of antro-pyloric and duodenal strictures; therefore, they should be considered an alternative to palliative resection in cases of advanced stage disease or poor general physical condition.

摘要

目的

评估自膨式金属支架在胃窦幽门和/或十二指肠狭窄再通中的应用价值。

材料与方法

我们报告了15例无法手术的胃窦幽门和/或十二指肠狭窄患者的治疗经验,这些患者在透视引导下经口植入了21枚自膨式金属支架(18枚裸支架和3枚覆膜支架)。患者中男性11例,女性4例,平均年龄65.3岁。15例患者中有14例患有胃窦幽门区和/或十二指肠恶性狭窄,其中原发性10例,继发性4例。仅1例为术后瘢痕形成导致的良性狭窄。狭窄长度为3至9厘米(平均5.4厘米),直径为0至4毫米(平均1.27毫米)。

结果

15例患者共置入21枚支架:所有病例技术成功,14例临床症状改善。未观察到短期并发症。平均随访4.3个月。2例患者分别在1个月和2个月后因肿瘤腹膜播散出现呕吐。另外2例患者分别在3个月和2个月后出现假体口侧肿瘤过度生长,需要再次置入同轴支架以跨越新的狭窄。治疗良性狭窄的患者在3个月后出现黄疸,需要行经皮肝内外胆管引流。

结论

自膨式金属支架是治疗胃窦幽门和十二指肠狭窄的一种安全有效的方法;因此,对于晚期疾病或全身状况较差的患者,应将其视为姑息性切除的替代方法。

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