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自膨式金属支架在治疗颈段食管和/或下咽狭窄中的应用

Self-expandable metal stents in the management of cervical oesophageal and/or hypopharyngeal strictures.

作者信息

Profili S, Meloni G B, Feo C F, Pischedda A, Bozzo C, Ginesu G C, Canalis G C

机构信息

Department of Radiology, University of Sassari, Sassari, Italy.

出版信息

Clin Radiol. 2002 Nov;57(11):1028-33. doi: 10.1053/crad.2002.0988.

DOI:10.1053/crad.2002.0988
PMID:12409115
Abstract

AIM

To assess the usefulness of self-expandable metal stents in the recanalization of cervical and/or hypopharyngeal strictures.

MATERIALS AND METHODS

We report our experience in 10 patients with inoperable cervical and/or hypopharyngeal strictures treated by implantation of 11 uncovered self-expandable metal stents inserted perorally under fluoroscopic guidance. The stent was placed in the hypopharynx and cervical oesophagus in 3 patients and cervical oesophagus alone in 7. There were 8 men and 2 women, mean age 70.2 years, range 45-85 years. All patients but two had malignant stricture caused by squamous cell carcinoma, in one case there was a benign postoperative stenosis secondary to laryngectomy, and in the last patient a local recurrence from thyroid cancer.

RESULTS

Eleven stents were placed in 10 patients: technical success was achieved in 9 cases while clinical improvement was obtained in 8 cases. Seven of ten patients had a rapid improvement of dysphagia. One patient had a distal misplacement of the prosthesis, while in the other two cases stent position was very proximal and interfered with swallowing. A mean 9-month follow-up was obtained (range 3-24 months). Four patients with malignant stricture developed proliferation of neoplastic tissue after 2-5 months. The only patient treated for a benign stricture developed inside proliferation of granulation tissue after 4 months.

CONCLUSION

Despite several technical difficulties and a high rate of late complications, recanalization of cervical oesophageal strictures by self-expandable metal stents allowed good palliation of symptoms. Stents proved to be effective and well tolerated palliative treatment also for hypopharyngeal stenoses.

摘要

目的

评估自膨式金属支架在治疗颈段和/或下咽狭窄再通中的作用。

材料与方法

我们报告了10例颈段和/或下咽狭窄无法手术的患者的治疗经验,这些患者在透视引导下经口植入了11枚裸化自膨式金属支架。3例患者的支架置于下咽和颈段食管,7例患者的支架仅置于颈段食管。患者中男性8例,女性2例,平均年龄70.2岁,年龄范围45 - 85岁。除2例患者外,所有患者均因鳞状细胞癌导致恶性狭窄,1例为喉切除术后继发的良性术后狭窄,最后1例为甲状腺癌局部复发。

结果

10例患者共植入11枚支架:9例技术成功,8例临床症状改善。10例患者中有7例吞咽困难迅速改善。1例患者假体远端移位,另外2例患者支架位置非常靠近近端,影响吞咽。平均随访9个月(范围3 - 24个月)。4例恶性狭窄患者在2 - 5个月后出现肿瘤组织增生。唯一接受良性狭窄治疗的患者在4个月后出现肉芽组织增生。

结论

尽管存在一些技术困难和较高的晚期并发症发生率,但自膨式金属支架对颈段食管狭窄进行再通可有效缓解症状。支架对下咽狭窄也证明是一种有效的、耐受性良好的姑息治疗方法。

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