伯利兹皮肤利什曼病的管理
The management of cutaneous leishmaniasis from Belize.
作者信息
Palmer R A, Tran D, Hepburn N C, Ashton R E
机构信息
Department of Dermatology, Royal Hospital Haslar, Gosport, UK, County Hospital, Lincoln, UK.
出版信息
Clin Exp Dermatol. 2001 Jan;26(1):16-20. doi: 10.1046/j.1365-2230.2001.00751.x.
We report 20 patients who contracted cutaneous leishmaniasis in Central and South America, 18 of them in Belize. The diagnosis was confirmed by the polymerase chain reaction (PCR) in 79% of those tested; the corresponding figure for histology was 62%, touch smear 46%, and culture 11%. Results of PCR can be falsely positive, so treatment should not be based on PCR alone. Of the 20 cases 18 were healed 6 weeks after intravenous sodium stibogluconate 20 mg/kg per day for 20 days. We present a management protocol.
我们报告了20例在中美洲和南美洲感染皮肤利什曼病的患者，其中18例在伯利兹。79%的受测患者通过聚合酶链反应（PCR）确诊；组织学确诊率为62%，触片检查为46%，培养为11%。PCR结果可能出现假阳性，因此不应仅基于PCR进行治疗。20例患者中有18例在每天静脉注射20mg/kg葡萄糖酸锑钠，持续20天后，6周内痊愈。我们提出了一个管理方案。
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