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对可能由怀孕母亲饮酒导致的致畸效应的分析。

An analysis of the teratagenic effects that could possibly be due to alcohol consumption by pregnant mothers.

作者信息

Chaudhuri J D

机构信息

Department of Anatomy, Faculty of Medicine, University Malaya, 50606, Kuala Lumpur, Malaysia.

出版信息

Indian J Med Sci. 2000 Oct;54(10):425-31.

Abstract

It can be concluded that alcohol is definitely harmful to the developing fetus. The effect can manifest in various ways, the most extreme of which is a condition called Fetal Alcohol Syndrome (FAS). The diagnosis of maternal alcoholism leading onto cases of FAS is difficult due to absence of accurate diagnostic tests. The diagnosis of FAS in a child is easier by a proper examination. There is no specific treatment of FAS in a child. The only management is by institution of corrective and rehabilitative measures. The exact mechanism of the teratogenic action of alcohol is not known. It is probably due to the harmful effect of alcohol on the epiblast layer of the bilaminar germ disc. In the absence of adequate knowledge regarding FAS, not much can be done to remedy the deleterious effects of alcohol. Hence, a word of advice to all pregnant women is to avoid drinking during pregnancy.

摘要

可以得出结论,酒精对发育中的胎儿绝对有害。这种影响可以以多种方式表现出来,最极端的情况是一种叫做胎儿酒精综合征(FAS)的病症。由于缺乏准确的诊断测试,诊断导致FAS病例的母亲酗酒很困难。通过适当检查,诊断儿童的FAS更容易。儿童FAS没有特定的治疗方法。唯一的管理方法是采取矫正和康复措施。酒精致畸作用的确切机制尚不清楚。这可能是由于酒精对双胚层胚盘的外胚层的有害影响。由于对FAS缺乏足够的了解,无法采取太多措施来补救酒精的有害影响。因此,给所有孕妇的一句忠告是在怀孕期间避免饮酒。

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