Zhang Y, Chu Y, Chen G
Institute of Hematology and Blood Diseases Hospital, CAMS and PUMC, Tianjin 300020.
Zhonghua Xue Ye Xue Za Zhi. 1998 Nov;19(11):573-5.
To analyze the clinical features and treatment outcomes of autoimmune hemolytic anemia (AIHA).
Coombs test positive AIHA patients were retrospectively analyzed.
Patients with AIHA were predominantly female, secondary AIHA accounted for 49% of the total cases, mainly associated with connective tissue diseases. In most cases of AIHA, the anti-red cell antibodies were IgG plus C3, while patients with IgG plus IgM had more severe clinical manifestations. The response rate of adrenocortical hormones and cyclosporin A (CsA) was 90.9%.
Adrenocorticosteroids is still the first choice of therapy for AIHA, CsA can improve the response rate.
分析自身免疫性溶血性贫血（AIHA）的临床特征及治疗效果。
对Coombs试验阳性的AIHA患者进行回顾性分析。
AIHA患者以女性为主，继发性AIHA占总病例的49%，主要与结缔组织病相关。在大多数AIHA病例中，抗红细胞抗体为IgG加C3，而IgG加IgM的患者临床表现更严重。肾上腺皮质激素和环孢素A（CsA）的有效率为90.9%。
肾上腺皮质激素仍是AIHA的首选治疗药物，CsA可提高有效率。
