急性四氯化碳和乙硫氨酸中毒时的大鼠肝脏同工酶
Rat liver isozymes in acute carbon tetrachloride and ethionine poisoning.
作者信息
Gazzaniga P P
出版信息
Enzyme. 1975;20(4):193-208. doi: 10.1159/000458941.
PMID:1126337
Abstract
Changes in protein elution patterns and among others in the distribution profiles of some isozymes, as the lysosomal acid phosphatase, the microsomal alkaline phosphatase, the cytoplasmic fraction of aspartate aminotransferase and some fractions of glucose-6-phosphate dehydrogenase and 6-phosphogluconate dehydrogenase, have been found in liver experimental fatty change induced in rats by carbon tetrachloride and ethionine. The possible meaning of these changes is discussed.
摘要
在四氯化碳和乙硫氨酸诱导的大鼠肝脏实验性脂肪变性中，发现了蛋白质洗脱模式的变化，以及某些同工酶（如溶酶体酸性磷酸酶、微粒体碱性磷酸酶、天冬氨酸氨基转移酶的细胞质部分以及葡萄糖-6-磷酸脱氢酶和6-磷酸葡萄糖酸脱氢酶的某些部分）分布图谱的变化。本文讨论了这些变化可能的意义。
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