睫状体光凝激光治疗疼痛性失明青光眼眼
Cyclodiode laser therapy for painful, blind glaucomatous eyes.
作者信息
Martin K R, Broadway D C
出版信息
Br J Ophthalmol. 2001 Apr;85(4):474-6. doi: 10.1136/bjo.85.4.474.
AIMS
To determine the ability of cyclodiode laser treatment to relieve discomfort in painful blind glaucomatous eyes.
METHODS
30 eyes underwent cyclodiode to reduce intraocular pressure (IOP) and relieve pain. Patients graded their pre-cyclodiode and post-cyclodiode pain.
RESULTS
After a minimum follow up of 6 months, a single cyclodiode treatment lowered mean IOP from 51 mm Hg (95% CI plus or minus 3.7 mm Hg) to 26 mm Hg (95% CI plus or minus 5.8 mm Hg) providing pain relief in 73.3% (22/30). After retreatment of six eyes, mean IOP was reduced to 22 (95% CI plus or minus 5.3) mm Hg and pain relief was obtained in 96.7% (29/30). For eyes achieving pain relief after one treatment, IOP was reduced by >30% in 81.0% (17/21). For eyes not achieving pain relief after one treatment, IOP was reduced by >30% in only 22.2% (2/9) (p=0.0042, Fisher's exact test).
CONCLUSION
Cyclodiode was highly successful in providing pain relief in painful blind hypertensive glaucomatous eyes. The best predictor of successful pain relief was IOP reduction of > 30% from baseline.
目的
确定睫状体光凝二极管激光治疗缓解盲性青光眼疼痛性眼不适的能力。
方法
30只眼睛接受睫状体光凝二极管激光治疗以降低眼压（IOP）并缓解疼痛。患者对睫状体光凝二极管激光治疗前和治疗后的疼痛进行分级。
结果
在至少随访6个月后，单次睫状体光凝二极管激光治疗使平均眼压从51 mmHg（95%置信区间±3.7 mmHg）降至26 mmHg（95%置信区间±5.8 mmHg），73.3%（22/30）的患者疼痛得到缓解。对6只眼睛进行再次治疗后，平均眼压降至22（95%置信区间±5.3）mmHg，96.7%（29/30）的患者疼痛得到缓解。对于单次治疗后疼痛得到缓解的眼睛，81.0%（17/21）的眼压降低>30%。对于单次治疗后未缓解疼痛的眼睛，只有22.2%（2/9）的眼压降低>30%（p = 0.0042，Fisher精确检验）。
结论
睫状体光凝二极管激光治疗在缓解盲性青光眼疼痛性眼的疼痛方面非常成功。疼痛缓解成功的最佳预测指标是眼压较基线降低>30%。
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