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洋葱伯克霍尔德菌及其他在囊性纤维化中具有重要意义的病原体对紫外线的敏感性。

Susceptibility of Burkholderia cepacia and other pathogens of importance in cystic fibrosis to u.v. light.

作者信息

Cairns G, Kerr K G, Beggs C B, Sleigh P A, Mooney L, Keig P, Donnelly J K

机构信息

Department of Microbiology, University of Leeds, Leeds, UK.

出版信息

Lett Appl Microbiol. 2001 Mar;32(3):135-8. doi: 10.1046/j.1472-765x.2001.00874.x.

DOI:10.1046/j.1472-765x.2001.00874.x
PMID:11264740
Abstract

To investigate the potential usefulness of u.v. germicidal irradiation (UVGI) in preventing the spread of Burkholderia cepacia, an important pathogen in cystic fibrosis (CF), the in-vitro susceptibility of B. cepacia to UVGI was determined. Five strains were exposed to UVGI from a 7.2-W source. Burkholderia cepacia was less susceptible to UVGI than other important CF-related pathogens, namely Staphylococcus aureus and Pseudomonas aeruginosa, but was more susceptible than Stenotrophomonas maltophilia. No strain of B. cepacia survived longer than an 8 s exposure to UVGI, with doses required to achieve 1 log reduction in bacterial numbers ranging from 28.3 to 57.5 J m(-2).

摘要

为研究紫外线杀菌照射(UVGI)在预防洋葱伯克霍尔德菌传播方面的潜在作用,洋葱伯克霍尔德菌是囊性纤维化(CF)中的一种重要病原体,测定了洋葱伯克霍尔德菌对UVGI的体外敏感性。将五株菌株暴露于来自7.2瓦光源的UVGI下。与其他重要的CF相关病原体(即金黄色葡萄球菌和铜绿假单胞菌)相比,洋葱伯克霍尔德菌对UVGI的敏感性较低,但比嗜麦芽窄食单胞菌更敏感。没有一株洋葱伯克霍尔德菌在暴露于UVGI 8秒以上后存活,使细菌数量减少1个对数所需的剂量范围为28.3至57.5 J m(-2)。

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