[Renal and extrarenal mechanisms of potassium homeostasis following a potassium load].

In rats, per os i.v. administration of 1.25 per cent KCl solution (840 mcEq/100 g.b.w.) increased concentration of potassium in the blood and tissues, as well as the urine excretion of potassium. The excretion rate depended on the amount of potassium load. After adrenalectomy and aldactone injection, the potassium excretion decreased. This, apparently, indicates that the adrenocortical steroids exert an influence on the transport of potassium. Hence, both the renal and extrarenal systems play an important role in the potassium homeostasis.