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[心脏停搏供体——扩大肾脏供体项目的新可能]

[Donors with non-beating hearts--a new possibility in expanding the kidney donor program].

作者信息

Treska V, Hasman D, Hes O, Kuntscher V

机构信息

Chirurgická klinika FN, Plzen-Lochotín.

出版信息

Rozhl Chir. 2000 Dec;79(12):622-5.

Abstract

In the Czech Republic in recent years a steady decline of renal transplantations was recorded due to shortage of organ donors. The authors present initial experience with the collection of organs from dead non heart beating donors (NHBD). In the course of less than two years this programme was introduced within the framework of a clinical experiment (grant IGA MofH CR ND/4781-3) at the Surgical Clinic, Faculty Hospital in Plzen. A total of 20 kidneys were collected from NHBD and another 12 kidneys were not collected, most frequently because of difficulties in communication and organization. The donors were grouped according to the Maastricht classification. The mean age of donors was 43.3 years, the mean period of warm ischaemia was 22 minutes and the serum creatinine level was 145 mumol/l. Of 20 collected kidneys a normal histological appearance was recorded in 14, the remainder had different degrees of damage due to inadequate rinsing. Based on hitherto assembled experience the authors emphasize perfect team collaboration in collection from NHBD and a precise technique of collection. The next stage of the clinical study will be the preparation proper for clinical transplantation of kidneys from NHBD.

摘要

近年来,由于器官捐献者短缺,捷克共和国的肾移植数量持续下降。作者介绍了从非心脏跳动死亡供体(NHBD)获取器官的初步经验。在不到两年的时间里,该项目在比尔森大学医院外科诊所的一项临床实验(资助编号IGA MofH CR ND/4781 - 3)框架内实施。总共从NHBD获取了20个肾脏,另外12个肾脏未获取,最常见的原因是沟通和组织方面的困难。供体根据马斯特里赫特分类法进行分组。供体的平均年龄为43.3岁,平均热缺血时间为22分钟,血清肌酐水平为145μmol/L。在获取的20个肾脏中,14个组织学外观正常,其余的因冲洗不充分有不同程度的损伤。基于目前积累的经验,作者强调在从NHBD获取器官时完美的团队协作以及精确的获取技术。临床研究的下一阶段将是为NHBD肾脏的临床移植做好充分准备。

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