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[一例采用多西他赛成功治疗的复发性乳腺癌病例]

[A case of recurrent breast cancer successfully treated with docetaxel].

作者信息

Nakagawa T, Kudo T, Onuki M, Seto T, Kamata S, Kiyosawa Y, Ogawa J

机构信息

Dept. of Breast and Endocrinologic Surgery, Nakadori General Hospital.

出版信息

Gan To Kagaku Ryoho. 2001 Mar;28(3):383-5.

Abstract

A 50-year-old female underwent mastectomy for left breast cancer in June, 1991. She received tamoxifen for 36 months and tegafur for 30 months as adjuvant therapy. In November 1997, liver, lung and para-aortic lymph node recurrences were found, and we treated her six times with docetaxel 60 mg. After the chemotherapy, a complete response (CR) of all metastatic lesions was achieved and her serum CA15-3 level was decreased. Adverse reactions were grade 4 neutropenia, grade 2 alopecia, fever, and grade 1 edema. She received medroxyprogesterone acetate after the chemotherapy and has been well without re-growth of any metastases for over eight months.

摘要

一名50岁女性于1991年6月因左乳腺癌接受了乳房切除术。她接受了36个月的他莫昔芬和30个月的替加氟作为辅助治疗。1997年11月,发现肝脏、肺部和腹主动脉旁淋巴结复发,我们用60毫克多西他赛对她进行了6次治疗。化疗后,所有转移病灶均达到完全缓解(CR),她的血清CA15-3水平下降。不良反应为4级中性粒细胞减少、2级脱发、发热和1级水肿。化疗后她接受了醋酸甲羟孕酮治疗,至今情况良好,超过八个月没有任何转移灶复发。

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